Promega Corporation

Signaling Pathway Analysis (Minimal Promoter-Driven) Firefly Luciferase Vectors

See All pGL4 Vectors
Creating a cell line with an indicator of a functional signaling pathway is useful for deciphering the components in a signaling pathway. These tools are made by insertion of multiple repeats of a response element upstream of a minimal promoter (minP). Promega has designed vectors that report the activity of a variety of pathways using the optimized luc2 firefly luciferase gene in the pGL4 backbone. These vectors also have a hygromycin resistance selectable marker, allowing use either in transient transfection experiments or for selection of a stable cell line.

Available vectors and the pathway...

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  • Prices valid for customers of Promega Brazil only
Product Size Conc. Catalog # *List Price Order QTY Add to Cart
pGL4.37[luc2P/ARE/Hygro] Vector
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pGL4.37[luc2P/ARE/Hygro] Vector  Components

  • pGL4.37[luc2P/ARE/Hygro] Vector

    E364A1 x 20μg
20μg
- E3641 R$ 1.430,00 Add to cart
pGL4.38[luc2P/p53 RE/Hygro] Vector
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pGL4.38[luc2P/p53 RE/Hygro] Vector  Components

  • pGL4.38[luc2P/p53 RE/Hygro] Vector

    E365A1 x 20μg
20μg
- E3651 R$ 1.430,00 Add to cart
pGL4.39[luc2P/ATF6 RE/Hygro] Vector
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pGL4.39[luc2P/ATF6 RE/Hygro] Vector  Components

  • pGL4.39[luc2P/ATF6 RE/Hygro] Vector

    E366A1 x 20μg
20μg
- E3661 Please Enquire
pGL4.40[luc2P/MRE/Hygro] Vector
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pGL4.40[luc2P/MRE/Hygro] Vector  Components

  • pGL4.40[luc2P/MRE/Hygro] Vector

    E413A1 x 20μg
20μg
- E4131 R$ 1.430,00 Add to cart
pGL4.41[luc2P/HSE/Hygro] Vector
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pGL4.41[luc2P/HSE/Hygro] Vector  Components

  • pGL4.41[luc2P/HSE/Hygro] Vector

    E375A1 x 20μg
20μg
- E3751 R$ 1.430,00 Add to cart
pGL4.42[luc2P/HRE/Hygro] Vector
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pGL4.42[luc2P/HRE/Hygro] Vector  Components

  • pGL4.42[luc2P/HRE/Hygro] Vector

    E400A1 x 20μg
20μg
- E4001 R$ 1.430,00 Add to cart
pGL4.43[luc2P/XRE/Hygro] Vector
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pGL4.43[luc2P/XRE/Hygro] Vector  Components

  • pGL4.43[luc2P/XRE/Hygro] Vector

    E412A1 x 20μg
20μg
- E4121 R$ 1.430,00 Add to cart
pGL4.44[luc2P/AP1 RE/Hygro] Vector
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pGL4.44[luc2P/AP1 RE/Hygro] Vector  Components

  • pGL4.44[luc2P/AP1 RE/Hygro] Vector

    E411A1 x 20μg
20μg
- E4111 R$ 1.430,00 Add to cart
pGL4.45[luc2P/ISRE/Hygro] Vector
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pGL4.45[luc2P/ISRE/Hygro] Vector  Components

  • pGL4.45[luc2P/ISRE/Hygro] Vector

    E414A1 x 20μg
20μg
- E4141 R$ 1.430,00 Add to cart
pGL4.47[luc2P/SIE/Hygro] Vector
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pGL4.47[luc2P/SIE/Hygro] Vector  Components

  • pGL4.47[luc2P/SIE/Hygro] Vector

    E404A1 x 20μg
20μg
- E4041 R$ 1.430,00 Add to cart
pGL4.48[luc2P/SBE/Hygro] Vector
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pGL4.48[luc2P/SBE/Hygro] Vector  Components

  • pGL4.48[luc2P/SBE/Hygro] Vector

    E367A1 x 20μg
20μg
- E3671 R$ 1.430,00 Add to cart
pGL4.49[luc2P/TCF-LEF RE/Hygro] Vector
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pGL4.49[luc2P/TCF-LEF RE/Hygro] Vector  Components

  • pGL4.49[luc2P/TCF-LEF RE/Hygro] Vector

    E461A1 x 20μg
20μg
- E4611 R$ 1.430,00 Add to cart
pGL4.52[luc2P/STAT5RE/Hygro] Vector
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pGL4.52[luc2P/STAT5RE/Hygro] Vector  Components

  • pGL4.52[luc2P/STAT5 RE/Hygro] Vector

    E465A1 x 20μg
20μg
- E4651 Please Enquire

pGL4.29[luc2P/CRE/Hygro] Vector

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pGL4.29[luc2P/CRE/Hygro] Vector

 Components

  • pGL4.29[luc2P/CRE/Hygro] Vector

    E847A1 x 20μg
20μg
- E8471 R$ 1.394,00 Add to cart

pGL4.30[luc2P/NFAT-RE/Hygro] Vector

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pGL4.30[luc2P/NFAT-RE/Hygro] Vector

 Components

  • pGL4.30[luc2P/NFAT-RE/Hygro] Vector

    E848A1 x 20μg
20μg
- E8481 R$ 1.394,00 Add to cart

pGL4.32[luc2P/NF-κB-RE/Hygro] Vector

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pGL4.32[luc2P/NF-κB-RE/Hygro] Vector

 Components

  • pGL4.32[luc2P/NF-κB-RE/Hygro] Vector

    E849A1 x 20μg
20μg
- E8491 R$ 1.394,00 Add to cart

pGL4.33[luc2P/SRE/Hygro] Vector

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pGL4.33[luc2P/SRE/Hygro] Vector

 Components

  • pGL4.33[luc2P/SRE/Hygro] Vector

    E134A1 x 20μg
20μg
- E1340 R$ 1.394,00 Add to cart

pGL4.34[luc2P/SRF-RE/Hygro] Vector

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pGL4.34[luc2P/SRF-RE/Hygro] Vector

 Components

  • pGL4.34[luc2P/SRF-RE/Hygro] Vector

    E135A1 x 20μg
20μg
- E1350 R$ 1.394,00 Add to cart


Available Separately

PRODUCT SIZE CONC CATALOG # *List Price ORDER QTY. Add to Cart

pGL4.23[luc2/minP] Vector

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pGL4.23[luc2/minP] Vector

 Components

  • pGL4.23[luc2/minP] Vector

    E841A1 x 20μg
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  • This product can be added to a

  • Helix Freezer

This product is available through the Promega Helix onsite stocking program in a –20°C Helix Freezer. The program offers numerous convenient solutions to meet your lab's needs. Helix Freezers are available in two sizes: 5.7 cubic ft. or 9.7 cubic ft.


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Request to add this product to your Helix »


20μg
- E8411 R$ 1.394,00 Add to cart

pGL4.24[luc2P/minP] Vector

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pGL4.24[luc2P/minP] Vector

 Components

  • pGL4.24[luc2P/minP] Vector

    E842A1 x 20μg
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  • This product can be added to a

  • Helix Freezer

This product is available through the Promega Helix onsite stocking program in a –20°C Helix Freezer. The program offers numerous convenient solutions to meet your lab's needs. Helix Freezers are available in two sizes: 5.7 cubic ft. or 9.7 cubic ft.


Click here to learn more about the Helix Collection »


Already a Helix Customer?

Request to add this product to your Helix »


20μg
- E8421 R$ 1.394,00 Add to cart

pGL4.25[luc2CP/minP] Vector

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pGL4.25[luc2CP/minP] Vector

 Components

  • pGL4.25[luc2CP/minP] Vector

    E843A1 x 20μg
20μg
- E8431 R$ 1.394,00 Add to cart

pGL4.26[luc2/minP/Hygro] Vector

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pGL4.26[luc2/minP/Hygro] Vector

 Components

  • pGL4.26[luc2/minP/Hygro] Vector

    E844A1 x 20μg
20μg
- E8441 R$ 1.394,00 Add to cart

pGL4.27[luc2P/minP/Hygro] Vector

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pGL4.27[luc2P/minP/Hygro] Vector

 Components

  • pGL4.27[luc2P/minP/Hygro] Vector

    E845A1 x 20μg
20μg
- E8451 R$ 1.394,00 Add to cart

pGL4.28[luc2CP/minP/Hygro] Vector

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pGL4.28[luc2CP/minP/Hygro] Vector

 Components

  • pGL4.28[luc2CP/minP/Hygro] Vector

    E846A1 x 20μg
20μg
- E8461 R$ 1.394,00 Add to cart

GloResponse™ CRE-luc2P HEK293 Cell Line

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GloResponse™ CRE-luc2P HEK293 Cell Line

 Components

  • GloResponse™ CRE-luc2P HEK293 Cell Line

    E850A2 x 1 vial
2 vials
- E8500 R$ 44.308,00 Add to cart

GloResponse™ NFAT-RE-luc2P HEK293 Cell Line

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GloResponse™ NFAT-RE-luc2P HEK293 Cell Line

 Components

  • GloResponse™ NFAT-RE-luc2P HEK293 Cell Line

    E851A2 x 1 vial
2 vials
- E8510 R$ 44.308,00 Add to cart

GloResponse™ NF-κB-RE-luc2P HEK293 Cell Line

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GloResponse™ NF-κB-RE-luc2P HEK293 Cell Line

 Components

  • NF-κB-luc2P HEK293 Cell Line

    E852A2 x 1 vial
2 vials
- E8520 R$ 44.308,00 Add to cart

You Also May Be Interested In

GenBank®/EMBL Accession Number

pGL4.37[luc2P/ARE/Hygro] Accession Number JQ858521; pGL4.37[luc2P/ARE/Hygro] Vector sequence text file.
pGL4.38[luc2P/p53 RE/Hygro] Accession Number JQ858522; pGL4.38[luc2P/p53 RE/Hygro] Vector sequence text file.
pGL4.39[luc2P/ATF6 RE/Hygro] Accession Number JQ858519; pGL4.39[luc2P/ATF6 RE/Hygro] Vector sequence text file.
pGL4.40[luc2P/MRE/Hygro] Accession Number JQ858515; pGL4.40[luc2P/MRE/Hygro] Vector sequence text file.
pGL4.41[luc2P/HSE/Hygro] Accession Number JQ858520; pGL4.41[luc2P/HSE/Hygro] Vector sequence text file.
pGL4.42[luc2P/HRE/Hygro] Accession Number JQ858518; pGL4.42[luc2P/HRE/Hygro] Vector sequence text file.
pGL4.43[luc2P/XRE/Hygro] Accession Number JQ858513; pGL4.43[luc2P/XRE/Hygro] Vector sequence text file.
pGL4.44[luc2P/AP1 RE/Hygro] Accession Number JQ858516; pGL4.44[luc2P/AP1 RE/Hygro] Vector sequence text file.
pGL4.45[luc2P/ISRE/Hygro] Accession Number JQ858514; pGL4.45[luc2P/ISRE/Hygro] Vector sequence text file.
pGL4.47[luc2P/SIE/Hygro] Accession Number JQ858512; pGL4.47[luc2P/SIE/Hygro] Vector sequence text file.
pGL4.48[luc2P/SBE/Hygro] Accession Number JQ858517; pGL4.48[luc2P/SBE/Hygro] Vector sequence text file.
pGL4.49[luc2P/TCF-LEF RE/Hygro] Accession Number JX099537; pGL4.49[luc2P/TCF-LEF RE/Hygro] Vector sequence text file.
pGL4.52[luc2P/STAT5 RE/Hygro] Accession Number JX206457; pGL4.52[luc2P/STAT5 RE/Hygro] Vector sequence text file.
pGL4.23[luc2/minP] Accession Number DQ904455; pGL4.23[luc2/minP] Vector sequence text file.
pGL4.24[luc2P/minP] Accession Number DQ904456; pGL4.24[luc2P/minP] Vector sequence text file.
pGL4.25[luc2CP/minP] Accession Number DQ904457; pGL4.25[luc2CP/minP] Vector sequence text file.
pGL4.26[luc2/minP/Hygro] Accession Number DQ904458; pGL4.26[luc2/minP/Hygro] Vector sequence text file.
pGL4.27[luc2P/minP/Hygro] Accession Number DQ904459; pGL4.27[luc2P/minP/Hygro] Vector sequence text file.
pGL4.28[luc2CP/minP/Hygro] Accession Number DQ904460; pGL4.28[luc2CP/minP/Hygro] Vector sequence text file.
pGL4.29[luc2P/CRE/Hygro] Accession Number DQ904461; pGL4.29[luc2P/CRE/Hygro] Vector sequence text file.
pGL4.30[luc2P/NFAT-RE/Hygro] Accession Number DQ904462; pGL4.30[luc2P/NFAT-RE/Hygro] Vector sequence text file.
pGL4.32[luc2P/NF-κB-RE/Hygro] Accession Number EU581860; pGL4.32[luc2P/NF-κB-RE/Hygro] Vector sequence text file.
pGL4.33[luc2P/SRE/Hygro] Accession Number FJ773212; pGL4.33[luc2P/SRE/Hygro] Vector sequence text file.
pGL4.34[luc2P/SRF-RE/Hygro] Accession Number FJ773213; pGL4.34[luc2P/SRF-RE/Hygro] Vector sequence text file.

Storage Conditions

Store at –20°C.

For product intended use please see Patents & Disclaimers tab.

pGL4.23[luc2/minP] Vector.Figure 1. pGL4.23[luc2/minP] Vector.
pGL4.24[luc2P/minP] Vector.Figure 2. pGL4.24[luc2P/minP] Vector.
pGL4.25[luc2CP/minP] Vector.Figure 3. pGL4.25[luc2CP/minP] Vector.
pGL4.26[luc2/minP/Hygro] Vector.Figure 4. pGL4.26[luc2/minP/Hygro] Vector.
pGL4.27[luc2P/minP/Hygro] Vector.Figure 5. pGL4.27[luc2P/minP/Hygro] Vector.
pGL4.28[luc2CP/minP/Hygro] Vector.Figure 6. pGL4.28[luc2CP/minP/Hygro] Vector.
pGL4.29[luc2P/CRE/Hygro] Vector.Figure 7. pGL4.29[luc2P/CRE/Hygro] Vector.
pGL4.30[luc2P/NFAT-RE/Hygro] Vector.Figure 8. pGL4.30[luc2P/NFAT-RE/Hygro] Vector.
pGL4.32[luc2P/NF-KB-RE/Hygro] Vector.Figure 9. pGL4.32[luc2P/NF-kappa-B-RE/Hygro] Vector.
pGL4.33[luc2P/SRE/Hygro] Vector.Figure 10. pGL4.33[luc2P/SRE/Hygro] Vector.
pGL4.34[luc2P/SRF-RE/Hygro] Vector.Figure 11. pGL4.34[luc2P/SRF-RE/Hygro] Vector.
pGL4.37[luc2P/ARE/Hygro] Vector.Figure 12. pGL4.37[luc2P/ARE/Hygro] Vector.
pGL4.38[luc2P/p53 RE/Hygro] Vector.Figure 13. pGL4.38[luc2P/p53 RE/Hygro] Vector.
pGL4.39[luc2P/ATF6 RE/Hygro] Vector.Figure 14. pGL4.39[luc2P/ATF6 RE/Hygro] Vector.
pGL4.40[luc2P/MRE/Hygro] Vector.Figure 15. pGL4.40[luc2P/MRE/Hygro] Vector.
pGL4.41[luc2P/HSE/Hygro] Vector.Figure 16. pGL4.41[luc2P/HSE/Hygro] Vector.
pGL4.42[luc2P/HRE/Hygro] Vector.Figure 17. pGL4.42[luc2P/HRE/Hygro] Vector.
pGL4.43[luc2P/XRE/Hygro] Vector.Figure 18. pGL4.43[luc2P/XRE/Hygro] Vector.
pGL4.44[luc2P/AP1 RE/Hygro] Vector.Figure 19. pGL4.44[luc2P/AP1 RE/Hygro] Vector.
pGL4.45[luc2P/ISRE/Hygro] Vector.Figure 20. pGL4.45[luc2P/ISRE/Hygro] Vector.
pGL4.44[luc2P/SIE/Hygro] Vector.Figure 21. pGL4.44[luc2P/SIE/Hygro] Vector.
pGL4.48[luc2P/SBE/Hygro] Vector.Figure 22. pGL4.48[luc2P/SBE/Hygro] Vector.
pGL4.49[luc2P/TCF-LEF RE/Hygro] Vector.Figure 23. pGL4.49[luc2P/TCF-LEF RE/Hygro] Vector.
pGL4.52[luc2P/STAT5 RE/Hygro] Vector.Figure 24. pGL4.52[luc2P/STAT5 RE/Hygro] Vector.

Use Restrictions

E3641, E3651, E3661, E4131, E3751, E4001, E4121, E4111, E4141, E4041, E3671, E4611, E4651, E8471, E8481, E8491, E1340, E1350, E8411, E8421, E8431, E8441, E8451, E8461, E8500, E8510, E8520 For Research Use Only. Not for Use in Diagnostic Procedures.

Patents - Disclaimers

E3641, E3651, E3661, E4131, E3751, E4001, E4121, E4111, E4141, E4041, E3671, E4611, E4651, E8471, E8481, E8491, E1340, E1350, E8411, E8421, E8431, E8441, E8451, E8461, E8500, E8510, E8520 BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If the researcher is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide the researcher with a full refund.
Researchers may use this product for research use only, no commercial use is allowed. "Commercial use" means any and all uses of this product and derivatives by a party for money or other consideration and may include but is not limited to use in: (1) product manufacture; and (2) to provide a service, information or data; and/or resale of the product or its derivatives, whether or not such product or derivatives are resold for use in research. Researchers shall have no right to modify or otherwise create variations of the nucleotide sequence of the luciferase gene except that researchers may: (1) create fused gene sequences provided that the coding sequence of the resulting luciferase gene has no more than four deoxynucleotides missing at the affected terminus compared to the intact luciferase gene sequence, and (2) insert and remove nucleic acid sequences in splicing research predicated on the inactivation or reconstitution of the luminescence of the encoded luciferase. No other use or transfer of this product or derivatives is authorized without the prior express written consent of Promega. In addition, researchers must either: (1) use luminescent assay reagents purchased from Promega for all determinations of luminescence activity of this product and its derivatives; or (2) contact Promega to obtain a license for use of the product and its derivatives. Researchers may transfer derivatives to others for research use provided that at the time of transfer a copy of this label license is given to the recipients and recipients agree to be bound by the terms of this label license. With respect to any uses outside this label license, including any diagnostic, therapeutic or prophylactic uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA. This label license relates to Promega patents and/or patent applications on improvements to the luciferase gene.

E3641, E3651, E3661, E4131, E3751, E4001, E4121, E4111, E4141, E4041, E3671, E4611, E4651, E8471, E8481, E8491, E1340, E1350, E8411, E8421, E8431, E8441, E8451, E8461, E8500, E8510, E8520 U.S. Pat. No. 5,670,356.

E3641, E3651, E3661, E4131, E3751, E4001, E4121, E4111, E4141, E4041, E3671, E4611, E4651, E8471, E8481, E8491, E1340, E1350, E8411, E8421, E8431, E8441, E8451, E8461, E8500, E8510, E8520 U.S. Pat. No. 8,008,006 and European Pat. No. 1341808.

E3641, E3651, E3661, E4131, E3751, E4001, E4121, E4111, E4141, E4041, E3671, E4611, E4651, E8471, E8481, E8491, E1340, E1350, E8411, E8451, E8461 U.S. Pat. No. 7,728,118.

E8471, E8481, E8411, E8421, E8431, E8441, E8451, E8461, E8500, E8510, E8520 Patent Pending.

E3641, E3651, E3661, E4131, E3751, E4001, E4121, E4111, E4141, E4041, E3671, E4611, E4651, E8471, E8481, E8491, E1340, E1350, E8411, E8421, E8431, E8441, E8451, E8461, E8500, E8510, E8520 The method of recombinant expression of Coleoptera luciferase is covered by U.S. Pat. Nos. 5,583,024, 5,674,713 and 5,700,673. A license (from Promega for research reagent products and from The Regents of the University of California for all other fields) is needed for any commercial sale of nucleic acid contained within or derived from this product.

E3671 Licensed under U.S. Pat. No. 6,100,032.

E8500, E8510, E8520 Commercial use of this cell line requires a license from AdVec Inc.

E8500, E8510, E8520 Use of Genetically Modified Microorganisms (GMM)
Information for European Customers: These products are genetically modified as described in Promega technical literature. As a condition of sale, use of this product must be in accordance with all applicable local guidelines on the contained use of genetically modified microorganisms, including the Directive 2009/41/EC of the European Parliament and of the Council.

E8500, E8510, E8520 HEK293 cells were obtained under license from AdVec Inc.

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